1. Access to a Key Building Block for the Prostaglandin Family via Stereocontrolled Organocatalytic Baeyer–Villiger Oxidation. Kejie Zhu, Sha Hu, Minjie Liu, Haihui Peng,*  Fen-Er Chen*. Angew. Chem. Int. Ed. 2019, 58, 9923 –9927(IF=12.257)

2. Small-Molecule Inhibitors of Necroptosis: Current Status and Perspectives. Chunlin Zhuang*,  Fener Chen*. J. Med. Chem. XXXX, XXX, XXX−XXX(IF=6.054)

3. Ligand-Based Design of Nondimethylphenyl-Diarylpyrimidines with Improved Metabolic Stability, Safety, and Oral Pharmacokinetic Profiles. Yali Sang, Sheng Han, Christophe Pannecouque, Erik De Clercq, Chunlin Zhuang*, Fener Chen*. J. Med. Chem. 2019, 62, 11430−11436(IF=6.054)

4. Improving the positional adaptability: structurebased design of biphenyl-substituted diaryltriazines as novel non-nucleoside HIV-1 reverse transcriptase inhibitors. Kaijun Jin, Minjie Liu, Chunlin Zhuang, Erik De Clercq, Christophe Pannecouque, Ge Meng*, Fener Chen*. Acta Pharmaceutica Sinica B. https://doi.org/10.1016/j.apsb.2019.09.007(IF=5.808)

5. Development of non-nucleoside reverse transcriptase inhibitors (NNRTIs): Our past twenty years. Chunlin Zhuang, Christophe Pannecouque, Erik De Clercq, Fener Chen*. Acta Pharmaceutica Sinica B. doi.org/10.1016/j.apsb.2019.11.010(IF=5.808)

6. Substituent Position-Controlled Stereoselectivity in Enzymatic Reduction of Diaryl- and Aryl(heteroaryl)methanones. Zhining Li, Zexu Wang, Yuhan Wang, Xiaofan Wu, Hong Lu,Zedu Huang,*  Fener Chen*. Adv. Synth. Catal. 2019, 361, 1859– 1865(IF=5.451)

7. Molecular Hybridization-Inspired Optimization of Diarylbenzopyrimidines as HIV‑1 Nonnucleoside Reverse Transcriptase Inhibitors with Improved Activity against K103N and E138K Mutants and Pharmacokinetic Profiles. Sheng Han, Yali Sang, Yan Wu,Yuan Tao, Christophe Pannecouque, Erik De Clercq, Chunlin Zhuang,*  Fen-Er Chen*. ACS Infect. Dis. XXXX, XXX, XXX−XXX(IF=4.911)

8. Synthesis and biological evaluation of dihydroquinazoline-2-amines as potent non-nucleoside reverse transcriptase inhibitors of wild-type and mutant HIV-1 strains. KaiJun Jin, YaLi Sang, Sheng Han, Erik De Clercq, Christophe Pannecouque, Ge Meng*, FenEr Chen *. European Journal of Medicinal Chemistry 176 (2019) 11-20(IF=4.833)

9. Conformational restriction design of thiophene-biphenyl-DAPY HIV-1 non-nucleoside reverse transcriptase inhibitors. Yali Sang, Sheng Han, Christophe Pannecouque, Erik De Clercq, Chunlin Zhuang*, Fener Chen *. European Journal of Medicinal Chemistry 182 (2019) 111603(IF=4.833)

10. Fragment hopping-based discovery of novel sulfinylacetamidediarylpyrimidines (DAPYs) as HIV-1 nonnucleoside reverse transcriptase inhibitors. Sheng Han, Yali Sang, YanWu, Yuan Tao, Christophe Pannecouque, Erik De Clercq, Chunlin Zhuang, *Fen-Er Chen*. European Journal of Medicinal Chemistry 185 (2020) 111874(IF=4.833)

11. Organocatalytic Asymmetric Domino oxa-Michael-Mannich-[1,3]-Amino Rearrangement Reaction of N-Tosylsalicylimines to #,#-Unsaturated Aldehydes by Diarylprolinol Silyl Ethers. Sha Hu, Jiaqi Wang, Guanxin Huang, Kejie Zhu,  Fener Chen. The Journal of Organic Chemistry. 10.1021/acs.joc.9b02939(IF=4.754)

12. Direct Synthesis of Substituted (Z)-Allylic Sulfones by Palladium-Catalyzed Sulfonylation of Vinylethylene Carbonates with Sodium Sulfinates. Miaolin K, Guanxin Huang, Li Ding, Jingjie Fang,  Fen-er Chen*. ChemCatChem 2019, 11, 4720–4724(IF=4.495)

13. Follow on-based optimization of the biphenyl-DAPYs as HIV-1 nonnucleoside reverse transcriptase inhibitors against the wild-type and mutant strains. Yali Sang, Sheng Han, Shuwen Han, Christophe Pannecouque, Erik De Clercq, Chunlin Zhuang, Fener Chen*. Bioorganic Chemistry 89 (2019) 102974(IF=3.926)

14. Fragment-based discovery of sulfur-containing diarylbenzopyrimidines as novel nonnucleoside reverse transcriptase inhibitors. Sheng Han, Yuan Lei, Christophe Pannecouque, Erik De Clercq, Chunlin Zhuang,*, Fener Chen*. Chinese Chemical Letters. https://doi.org/10.1016/j.cclet.2019.11.020(IF=3.839)

15. Ketoreductase catalyzed stereoselective bioreduction of α-nitro ketones. Zexu Wang, Xiaofan Wu, Zhining Li, Zedu Huang *,  Fener Chen*. Org. Biomol. Chem., 2019, 17, 3575–3580(IF=3.49)

16. A Formal Synthesis of Camptothecin via a Photocatalytic Decarboxylative Radical Addition. Qian Liu, Guanxin Huang, Minjie Liu, Fener Chen*. Eur. J. Org. Chem. 2019, 6024–6027(IF=3.029)

17. A Concise Total Sythesis of (±) Camptothecin. Qian Liu, Guangxin Huang, Meijie Liu, Fener Chen*. Synthesis 2019, 51,3506-3510(IF=2.867)

18. 连续流微反应技术在药物合成中的应用研究进展.化工进展. 程荡. 陈芬儿. 2019 年第38 卷第1 期